Traumatic Brain Injury—Everyone is at Risk!

What is ProTECT?

ProTECT III is a research study designed to see if progesterone (a hormone normally found in our bodies) can reduce the amount of brain damage caused from a traumatic brain injury (TBI). Small studies in humans suggest that progesterone, given immediately after a TBI, may help treat brain injuries by reducing brain swelling and damage.

Why do this study?

There is no specific drug treatment for traumatic brain injury. The reason for doing this study is to find out if progesterone is safe, and if it works better than standard medical care alone in reducing brain damage caused from a TBI. If progesterone helps brain injury patients get better, it will be a big improvement in TBI treatment.

What hospitals will be involved with this study?

The University of Arizona's Arizona Emergency Medicine Research Center is participating in the ProTECT study with trauma centers in the Phoenix area and in Tucson. The hospitals involved in ProTECT include:

• University Medical Center, Tucson
• Maricopa Medical Center, Phoenix
• Banner Good Samaritan Medical Center, Phoenix
• Scottsdale Healthcare Osborn, Scottsdale

There will also be hospitals across the country participating in the study.